Microwave-assisted cascade strategy for the synthesis of indolo[2,3-b]quinolines from 2-(Phenylethynyl)anilines and aryl isothiocynates

Ali, Wajid ; Dahiya, Anjali ; Pandey, Ramdhari ; Alam, Tipu ; Patel, Bhisma K. (2017) Microwave-assisted cascade strategy for the synthesis of indolo[2,3-b]quinolines from 2-(Phenylethynyl)anilines and aryl isothiocynates The Journal of Organic Chemistry, 82 (4). pp. 2089-2096. ISSN 0022-3263

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Official URL: https://pubs.acs.org/doi/abs/10.1021/acs.joc.6b029...

Related URL: http://dx.doi.org/10.1021/acs.joc.6b02912

Abstract

The in situ generated o-alkynylthioureas obtain by reacting 2-(phenylethynyl)anilines and aryl isothiocynates undergo efficient cascade cyclization in the presence of Ag2CO3 to form indoloquinolines under microwave heating. The present tandem process allows the generation of a variety of indolo[2,3-b]quinolines derivatives in good to moderate yields with a wide functional group tolerance.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:114016
Deposited On:30 Apr 2018 12:18
Last Modified:30 Apr 2018 12:18

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