Properties of some diuridine phosphate analogues

Patel, Bhisma K. ; Thomson, James B. ; Jimenez, Victor ; Eckart, Klaus ; Fxkstein, Fritz (1997) Properties of some diuridine phosphate analogues Nucleosides and Nucleotides, 16 (7-9). pp. 1443-1446. ISSN 0732-8311

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Official URL: https://www.tandfonline.com/doi/abs/10.1080/073283...

Related URL: http://dx.doi.org/10.1080/07328319708006202

Abstract

The hydrolytic stability of oligoribonucleotides containing 2′- amino nucleophile is due to poor leaving characteristic of 5′-nucleoside, replacement of 5′-leaving group by thio or amino results in considerable instability towards hydrolysis.

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