Leukocyte derived chemotaxin 2 (ALECT2) amyloidosis

Kulkarni, Uday P. ; Valson, Anna ; Korula, Anila ; Mathews, Vikram (2015) Leukocyte derived chemotaxin 2 (ALECT2) amyloidosis Mediterranean Journal of Hematology and Infectious Diseases, 7 (1). Article ID e2015043-3 pages. ISSN 2035-3006

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Official URL: http://www.mjhid.org/index.php/mjhid/article/view/...

Related URL: http://dx.doi.org/10.4084/mjhid.2015.043


We describe the first case from India of ALECT2 amyloidosis. An adult Punjabi male presented with progressive renal dysfunction and non-nephrotic range proteinuria. Serum protein electrophoresis and Immunofixation were normal, with mildly elevated serum free light chain ratio. Renal biopsy confirmed the presence of amyloid. Immunohistochemistry was negative for monoclonal light chains. Proteomic analysis confirmed the presence of ALECT2 amyloid. The present case highlights the need for confirmatory testing for typing of amyloid.

Item Type:Article
Source:Copyright of this article belongs to PAGEPress.
Keywords:Amyloidosis; ALECT2; Renal Amyloid; Ethnic Variation; Treatment
ID Code:113911
Deposited On:07 Jun 2018 11:59
Last Modified:07 Jun 2018 12:22

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