Supramolecular ensemble of tetraphenylcyclopentadienone derivative and HgO nanoparticles: A one-pot approach for the synthesis of quinoline and quinolone derivatives

Abstract

Electron deficient tetraphenylcyclopentadienone appended with thiophene has been designed and synthesized which exihibits aggregation induced emission enhancement (AIEE) to form fluorescent assemblies in aqueous media. These emissive aggregates exhibit mercury induced emission enhancement in aqueous media and serve as reactors for the generation of mercury oxide nanoparticles. Further, the in situ generated supramolecular ensemble of tetraphenylcyclopentadienone aggregates and HgO nanomaterial show high catalytic efficiency in the reactions for the synthesis of N‐heterocyclic derivatives through ortho C−H functionalization of unprotected anilines. In addition, this catalytic system has been utilized for the kynurenic acid methyl esters (KYNA methyl ester) derivatives based non‐steroidal anti‐inflammatory drug through C−H functionalization strategy which is unprecedented in the literature.