Sahoo, Bankanidhi ; Goswami, Mithun ; Nag, Suman ; Maiti, Sudipta (2007) Spontaneous formation of a protein corona prevents the loss of quantum dot fluorescence in physiological buffers Chemical Physics Letters, 445 (4-6). pp. 217-220. ISSN 0009-2614
Full text not available from this repository.
Official URL: https://www.sciencedirect.com/science/article/abs/...
Related URL: http://dx.doi.org/10.1016/j.cplett.2007.07.075
Abstract
We report that proteins in physiological buffers spontaneously attach to polyethylene glycol coated fluorescent quantum dots (QDs) and strongly inhibit the gradual loss of QD fluorescence. This interaction does not strongly depend on the nature or solubility of the proteins tested (amyloid beta, barstar, cytochrome c, bovine serum albumin and lysozyme). Fluorescence correlation spectroscopy shows that each QD acquires a ‘corona’ of ∼100 protein molecules, which confers protection against ionic attacks in aqueous solutions. This effect would be important for any biological application, and also offers a potential in vitro assay for soluble proteins.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 112915 |
| Deposited On: | 24 May 2018 11:42 |
| Last Modified: | 24 May 2018 11:42 |
Repository Staff Only: item control page
