Paramagnetic probes in membrane biophysics

Sankaram, M. B. ; Easwaran, K. R. K. (1985) Paramagnetic probes in membrane biophysics Proceedings of the Indian Academy of Sciences - Chemical Sciences, 95 (1-2). pp. 103-115. ISSN 0253-4134

PDF - Publisher Version

Official URL:

Related URL:


The use of paramagnetic probes in membrane research is reviewed. Electron paramagnetic resonance studies on model and biological membranes doped with covalent and non-covalent spin-labels have been discussed with special emphasis on the methodology and the type of information obtainable on several important phenomena like membrane fluidity, lipid flip-flop, lateral diffusion of lipids, lipid phase separation, lipid bilayer phase transitions, lipid-protein interactions and membrane permeability. Nuclear magnetic resonance spectroscopy has also been effectively used to study the conformations of cation mediators across membranes and to analyse in detail the transmembrane ionic motions at the mechanistic level.

Item Type:Article
Source:Copyright of this article belongs to Indian Academy of Sciences.
Keywords:Membranes; Electron Paramagnetic Resonance; Nuclear Magnetic Resonance; Spinlabels; Paramagnetic Probes
ID Code:11130
Deposited On:09 Nov 2010 03:54
Last Modified:16 May 2016 20:38

Repository Staff Only: item control page