Form I of desloratadine, a tricyclic antihistamine

Bhatt, P. M. ; Desiraju, G. R. (2006) Form I of desloratadine, a tricyclic antihistamine Acta Crystallographica Section C: Crystal Structure Communications, 62 . o362-o363. ISSN 0108-2701

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The title compound [systematic name: 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[4,5]cyclohepta[2,1-b]pyridine], C19H19ClN2, was crystallized from ethyl acetate. The interesting feature of the reported structure is that it does not contain any strong hydrogen bonds, although the molecule contains a secondary NH group, which is a good hydrogen-bond donor.

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ID Code:10950
Deposited On:09 Nov 2010 04:26
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