Lipid-motor interactions: soap opera or symphony?

Pathak, Divya ; Mallik, Roop (2017) Lipid-motor interactions: soap opera or symphony? Current Opinion in Cell Biology, 44 . pp. 79-85. ISSN 0955-0674

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Intracellular transport of organelles can be driven by multiple motor proteins that bind to the lipid membrane of the organelle and work as a team. We review present knowledge on how lipids orchestrate the recruitment of motors to a membrane. Looking beyond recruitment, we also discuss how heterogeneity and local mechanical properties of the membrane may influence function of motor-teams. These issues gain importance because phagocytosed pathogens use lipid-centric strategies to manipulate motors and survive in host cells.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:109338
Deposited On:10 Oct 2017 13:22
Last Modified:10 Oct 2017 13:22

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