Identification of bovine brain calcium binding proteins

Tokuda, Masaaki ; Khanna, Navin C. ; Waisman, David M. (1987) Identification of bovine brain calcium binding proteins Cell Calcium, 8 (3). pp. 229-239. ISSN 0143-4160

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Three peaks of calcium binding activity have been identified by the Chelex-100 calcium binding assay of the fractions from DEAE cellulose chromatography of 100,000 × g supernatant of bovine brain. These calcium binding activity peaks have been subjected to extensive purification and three novel calcium binding proteins (Mr 27,000, Mr 48,000 and Mr 63,000) and two previously characterized proteins (calcineurin and calmodulin) have been identified as components of calcium binding activity peaks. Analysis of the calcium binding properties of the novel proteins by equilibrium dialysis suggests these proteins may be intracellular calcium receptors.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:109130
Deposited On:09 Mar 2018 12:14
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