Bhattacharyya, Suvendra N. ; Filipowicz, Witold (2007) Argonautes and Company: sailing against the wind Cell, 128 (6). pp. 1027-1028. ISSN 0092-8674
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Official URL: http://www.cell.com/cell/fulltext/S0092-8674(07)00...
Related URL: http://dx.doi.org/10.1016/j.cell.2007.02.033
Abstract
The 3′-untranslated region (UTR) of mRNA is crucial for posttranscriptional regulation. In this issue, Vasudevan and Steitz (2007)) report a new function for AGO2 and FXR1—two proteins that have been linked to the regulation of microRNAs and translation repression. AGO2 and FXR1 bind to the AU-rich element in the 3′-UTR of TNFα mRNA, unexpectedly activating its translation in a cell growth-dependent manner.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 108153 |
| Deposited On: | 01 Feb 2018 11:12 |
| Last Modified: | 01 Feb 2018 11:12 |
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