8-amino(2-aminoethyl)-2'-deoxyadenosine incorporation into DNA by solid phase synthesis

Parkash, T. P. ; Ganesh, K. N. (1993) 8-amino(2-aminoethyl)-2'-deoxyadenosine incorporation into DNA by solid phase synthesis Bioorganic & Medicinal Chemistry Letters, 3 (4). pp. 689-692. ISSN 0960-894X

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S09608...

Related URL: http://dx.doi.org/10.1016/S0960-894X(01)81255-5

Abstract

Solid phase synthesis of modified oligonucleotide 5 containing 8-amino(2-aminoethyl)-2'-deoxyadenosine unit is reported using trifluoroacetyl as a C8-side chain amino protector. Solid phase synthesis of oligonucleotides 1, 2 containing 8-amino(2-aminoethyl)-2'-deoxyadenosine unit is demonstrated using trifluroacetyl as a C8 side chain amino protector.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:10785
Deposited On:09 Nov 2010 04:55
Last Modified:31 May 2011 10:00

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