Antony, Justin S. ; Ojurongbe, Olusola ; Meyer, Christian G. ; Thangaraj, Kumarasamy ; Mishra, Anshuman ; Kremsner, Peter G. ; Velavan, Thirumalaisamy P. (2015) Correlation of interleukin-6 levels and lectins during Schistosoma haematobium infection Cytokine, 76 (2). pp. 152-155. ISSN 1043-4666
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.cyto.2015.04.019
Abstract
Urogenital schistosomiasis caused by Schistosoma haematobium induces a Th2 immune response, including expression of Interleukin-6. IL-6 confers protection from experimental Schistosoma-induced pulmonary hypertension and modulates production of Mannose-binding Lectin (MBL) and other lectins. We studied IL-6 levels in schistosomiasis and its effect on lectins production. Elevated IL-6 levels occurred in cases, compared to controls. IL-6 correlated with the lectins MBL, ficolin-2 and Collectin Kidney-1 (CL-K1) in cases, but correlated inversely in controls. The study shows that IL-6 levels are elevated in individuals infected with urogenital schistosomiasis. IL-6 was also found to be correlated with the production of lectins in S. haematobium infection. A similar correlation between IL-6 and MBL was observed during visceral leishmaniasis.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | IL-6; MBL; Ficolin-2; CL-K1; Schistosomiasis |
| ID Code: | 107747 |
| Deposited On: | 17 Jul 2017 06:26 |
| Last Modified: | 17 Jul 2017 06:26 |
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