Synthesis of site-specific oligonucleotide-polyamine conjugates

Prakash, T. P. ; Barawkar, Dinesh A. ; Kumar, Vaijayanti ; Ganesh, K. N. (1994) Synthesis of site-specific oligonucleotide-polyamine conjugates Bioorganic & Medicinal Chemistry Letters, 4 (14). pp. 1733-1738. ISSN 0960-894X

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S09608...

Related URL: http://dx.doi.org/10.1016/S0960-894X(00)80371-6

Abstract

Synthesis of 5-Me-dC-amidite regiospecifically tethered at C4, with triethylenetetramine (8) and spermine (9) and their site specific incorporation into DNA to obtain oligonucleotide-polyamine conjugates (10-15) is reported.

Item Type:Article
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ID Code:10774
Deposited On:09 Nov 2010 04:56
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