How specific is the first recognition step of homologous recombination?

Rao, Basuthkar J. ; Chiu, SungKay ; Bazemore, Laura R. ; Reddy, Gurucharan ; Radding, Charles M. (1995) How specific is the first recognition step of homologous recombination? Trends in Biochemical Sciences, 20 (3). pp. 109-113. ISSN 0968-0004

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0968-0004(00)88976-8

Abstract

The Escherichia coli RecA protein promotes homologous recognition in base triplets via non-Watson-Crick bonds that differ from those formed nonenzymically from DNA consisting of runs of purines or pyrimidines. Base substitutions reveal recognition to be permissive, consistent with a search for homology that achieves speed at the cost of precision.

Item Type:Article
Source:Copyright of this article belongs to Elsevier.
ID Code:107470
Deposited On:15 Jun 2017 11:01
Last Modified:15 Jun 2017 11:01

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