Bone mineral parameters in healthy young Indian adults with optimal vitamin D availability

Tandon, N. ; Marwaha, R. K. ; Kalra, S. ; Gupta, Nandita ; Dudha, A. ; Kochupillai, N. (2003) Bone mineral parameters in healthy young Indian adults with optimal vitamin D availability The National Medical Journal of India, 16 (6). pp. 298-302. ISSN 0970-258X

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Abstract

Background: Several recent studies indicate a marked prevalence of vitamin D deficiency in asymptomatic, apparently healthy urban subjects from different socioeconomic groups in north India. Methods: To further examine this trend, we studied 40 men and 50 women, 20–30 years of age, from the Indian paramilitary forces. These individuals consume a nutritious, high-protein diet, have optimal exposure to sunlight and undertake strenuous outdoor physical exercise. Results: The mean serum calcium, phosphorus and alkaline phosphatase levels were normal in both men and women. The mean (SD) serum intact parathyroid hormone and 25-hydroxy-vitamin D3 levels were 19.3 (8.2) pg/ml and 18.4 (5.3) ng/ml in men, and 11.9 (6.6) pg/ml and 25.3 (7.4) ng/ml in women. Bone mineral density estimated in 20 men and 22 women revealed that in comparison with white Caucasians, 35%–50% of men and 14%–32% of women were osteopenic at different sites, while an additional 10% of men had osteoporosis of the lumbar spine. Conclusion: We found that with optimal nutrition, good sunlight exposure and regular physical exercise, healthy young individuals have normal bone and mineral biochemical values. The reasons for the abnormalities detected in bone mineral density in them needs further study. The impact of childhood nutrition on accumulation of peak bone mass may contribute to our findings. There is a need for establishing normative bone mineral density data for Indians.

Item Type:Article
Source:Copyright of this article belongs to All India Institute of Medical Sciences.
ID Code:107076
Deposited On:24 Jun 2017 14:41
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