Alkyne [2 + 2 + 2]-cyclotrimerization approach for synthesis of 6,7-cyclopropylallocolchicinoids

More, Atul A. ; Ramana, Chepuri V. (2016) Alkyne [2 + 2 + 2]-cyclotrimerization approach for synthesis of 6,7-cyclopropylallocolchicinoids Journal of Organic Chemistry, 81 (8). pp. 3400-3406. ISSN 0022-3263

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Official URL: http://pubs.acs.org/doi/abs/10.1021/acs.joc.6b0002...

Related URL: http://dx.doi.org/10.1021/acs.joc.6b00020

Abstract

Employing a cobalt-catalyzed [2 + 2 + 2] alkyne cyclotrimerization as the final step, the short and efficient synthesis of cyclopropylallocolchicinoid and its analogues having functional group variations at C9 and/or C10 and C11 of ring C has been accomplished.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:105876
Deposited On:01 Feb 2018 16:49
Last Modified:01 Feb 2018 16:49

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