Ir(III)-Catalyzed carbenoid functionalization of benzamides: Synthesis of N-methoxyisoquinolinediones and N-methoxyisoquinolinones

Phatake, Ravindra S. ; Patel, Pitambar ; Ramana, Chepuri V. (2016) Ir(III)-Catalyzed carbenoid functionalization of benzamides: Synthesis of N-methoxyisoquinolinediones and N-methoxyisoquinolinones Organic Letters, 18 (12). pp. 2828-2831. ISSN 1523-7060

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Official URL: http://pubs.acs.org/doi/abs/10.1021/acs.orglett.6b...

Related URL: http://dx.doi.org/10.1021/acs.orglett.6b01072

Abstract

A mild and efficient Ir(III)-catalyzed C–H carbenoid functionalization strategy has been developed to access N-methoxyisoquinolinediones and N-methoxyisoquinolinones. The reaction proceeds efficiently in high yield at room temperature over a broad range of substrates without requirement of any additional oxidants or a base.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:105875
Deposited On:01 Feb 2018 16:49
Last Modified:01 Feb 2018 16:49

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