Cobalt(II)-catalyzed direct acetylation of alcohols with acetic acid

Velusamy, Subbarayan ; Borpuzari, Sarbani ; Punniyamurthy, T. (2005) Cobalt(II)-catalyzed direct acetylation of alcohols with acetic acid Tetrahedron, 61 (8). pp. 2011-2015. ISSN 0040-4020

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tet.2005.01.006

Abstract

Cobalt(II) chloride hexahydrate (CoCl2·6H2O) efficiently catalyzes the acetylation of alcohols with AcOH in high yields. This protocol is also effective with other carboxylic acids, trifluoroacetic acid, propanoic acid, phenylacetic acid and benzoic acid, affording the corresponding acylated products in moderate to good yields. Removal of water is not necessary in these reactions. The catalyst can be filtered and recycled without loss of activity.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Acylation; Alcohol; Carboxylic Acid; Cobalt(II) Chloride; Catalyst
ID Code:105857
Deposited On:22 Jun 2017 10:38
Last Modified:22 Jun 2017 10:38

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