An expeditious enantiospecific synthesis of (+)-2-hydroxy-exo-brevicomin

Prasad, Kavirayani R. ; Anbarasan, Pazhamalai (2006) An expeditious enantiospecific synthesis of (+)-2-hydroxy-exo-brevicomin Synlett, 2006 (13). pp. 2087-2088. ISSN 0936-5214

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Official URL: https://www.thieme-connect.de/DOI/DOI?10.1055/s-20...

Related URL: http://dx.doi.org/10.1055/s-2006-948190

Abstract

An expeditious approach for the synthesis of Western pine beetle pheromone 2-hydroxy-exo-brevicomin from natural chiral pool L-(+)-tartaric acid was achieved. The key step involves a highly diastereoselective reduction of a keto-Weinreb amide and further elaboration to the title compound in high yields with complete stereocontrol.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers Inc.
Keywords:Pheromone; 2-Hydroxy-exo-brevicomin; Tartaric Acid; Stereoselective Reduction
ID Code:105839
Deposited On:21 Dec 2017 12:06
Last Modified:21 Dec 2017 12:06

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