Enantiodivergent total synthesis of microcarpalide from L-tartaric acid

Prasad, Kavirayani R. ; Penchalaiah, Kamala (2011) Enantiodivergent total synthesis of microcarpalide from L-tartaric acid Tetrahedron, 67 (23). pp. 4268-4276. ISSN 0040-4020

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tet.2011.03.102

Abstract

Stereoselective approach for the synthesis of both enantiomers of bio-active decanolactone microcarpalide is described from L-tartaric acid. The synthesis of the key intermediates en route to the natural product is achieved from L-tartaric acid involving the elaboration of γ-hydroxy amide derived from tartaric acid and ring opening of an epoxide derived from tartaric acid.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Decanolide; Microcarpalide; Tartaric Acid; Total Synthesis
ID Code:105699
Deposited On:21 Dec 2017 12:03
Last Modified:21 Dec 2017 12:03

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