Total synthesis of (−)-ent-pachastrissamine (ent-Jaspine B)

Prasad, Kavirayani R. ; Penchalaiah, Kamala (2011) Total synthesis of (−)-ent-pachastrissamine (ent-Jaspine B) Tetrahedron: Asymmetry, 22 (13). pp. 1400-1403. ISSN 0957-4166

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetasy.2011.07.010

Abstract

The total synthesis of the enantiomer of the tetrahydrofuran containing natural product Jaspine B is reported. The key reactions in the synthesis include formation of the tetrahydrofuran unit by an acid mediated Williamson etherification and a subsequent elaboration with an olefin cross metathesis reaction.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:105697
Deposited On:21 Dec 2017 12:05
Last Modified:21 Dec 2017 12:05

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