Tunable surface modification of silica nanoparticles through 'click' chemistry

Abstract

Tuning the surface functionality of silica nanoparticles through a 'click' chemistry-based protocol is demonstrated. Pyrene, a fluorophore that displays excimer emission specifically at higher density/concentration is chosen for highlighting the fidelity of surface functionalization. The UV-visible absorbance of the pyrene chromophore capping the nanoparticle is used to determine the amount of pyrene units present on the surface of a silica nanoparticle.