One-step synthesis of C-2 dialkylamino-substituted 2',3'-O-anhydro-lyxo-uridines: first report on the opening of 2,2'-O-anhydro-bridge of 2,2'-O-anhydrouridine by secondary amines

Sakthivel, Kandasamy ; Bera, Sanjib ; Pathak, Tanmaya (1993) One-step synthesis of C-2 dialkylamino-substituted 2',3'-O-anhydro-lyxo-uridines: first report on the opening of 2,2'-O-anhydro-bridge of 2,2'-O-anhydrouridine by secondary amines Tetrahedron, 49 (45). pp. 10387-10392. ISSN 0040-4020

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4020(01)80564-0

Abstract

Secondary amines successfully opened the 2,2'-O-anhydro-bridge of 2,2'-O-anhydrouridines 8a and 8b in presence of 3'-O-mesyl group to produce compounds 10a-13a and 10b-13b, a new class of isocytidine derivatives.

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