Bera, Sanjib ; Sakthivel, Kandasamy ; Pathak, Tanmaya (1995) 3'-deoxy-3'-(vinylsulphonyl)thymidine - a new reactive analogue of AZT: its synthesis and reactivities towards various nucleophiles Tetrahedron, 51 (28). pp. 7857-7866. ISSN 0040-4020
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Official URL: http://www.sciencedirect.com/science/article/pii/0...
Related URL: http://dx.doi.org/10.1016/0040-4020(95)00403-U
Abstract
A reactive triatomic analogue of AZT, 3'-deoxy-3'-(vinylsulphonyl)thymidine has been synthesised from easily accessible starting material. The vinyl-sulphone nucleoside was reacted with a variety of nucleophiles to generate new classes of modified nucleosides where the functional groups were attached to the C-3' of a nucleoside through flexible ethyl sulphone spacer.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 104279 |
| Deposited On: | 16 Mar 2017 12:20 |
| Last Modified: | 16 Mar 2017 12:20 |
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