Synthesis and synthetic applications of 1-(3-O-tosyl-β-D-glucopyranosyl) thymines: toward new classes of hexopyranosyl pyrimidines

Deshpande, Sachin G. ; Pathak, Tanmaya Synthesis and synthetic applications of 1-(3-O-tosyl-β-D-glucopyranosyl) thymines: toward new classes of hexopyranosyl pyrimidines Tetrahedron Letters, 45 (10). pp. 2255-2258. ISSN 0040-4039

Full text not available from this repository.

Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2003.12.153

Abstract

1-(2,4,6-Tri-O-acetyl-3-O-tosyl-β-D-glucopyranosyl) thymine has been synthesized by combining thymine with the appropriate carbohydrate. The availability of this key nucleoside made possible the synthesis of 2,2′-O-anhydro-(4,6-O-phenylmethylene-β-D-altropyranosyl) thymine and 1-(2,3-O-anhydro-4,6-O-phenylmethylene-β-D-mannopyranosyl) thymine. A wide range of modified hexopyranosyl nucleosides can be easily prepared from these functionalized starting materials.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Hexopyranosyl; Nucleosides; Modified; Allopyranosyl; Altropyranosyl; Azidonucleosides; Thionucleosides; Aminonucleosides
ID Code:104198
Deposited On:17 Mar 2017 09:17
Last Modified:17 Mar 2017 09:17

Repository Staff Only: item control page