A tandem Michael–SN2-mediated general route to six-membered heterocycles and carbocycles

Atta, Ananta Kumar ; Pathak, Tanmaya (2010) A tandem Michael–SN2-mediated general route to six-membered heterocycles and carbocycles European Journal of Organic Chemistry (35). pp. 6810-6819. ISSN 1434-193X

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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/ejoc.20...

Related URL: http://dx.doi.org/10.1002/ejoc.201000941

Abstract

A powerful, flexible, and stereoselective general strategy for the construction of chirally pure six-membered heterocycles and carbocycles by utilizing a tandem Michael–SN2 sequence is described. The strategy avoids the tedious synthesis of separate starting materials prior to cyclization. The expedient and general strategy, which is virtually untapped until now, will enrich the arsenal of synthetic chemists for the preparation of cyclic compounds.

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Deposited On:17 Mar 2017 11:46
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