Ghosh, Anindya Sundar ; Ahamed, Jasimuddin ; Chauhan, Kamlesh K. ; Kundu, Manikuntala (1998) Involvement of an efflux system in high-level fluoroquinolone resistance of Shigella dysenteriae Biochemical and Biophysical Research Communications, 242 (1). pp. 54-56. ISSN 0006-291X
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1006/bbrc.1997.7902
Abstract
Shigella dysenteriaerepresent one of the growing list of antibiotic-resistant bacteria. Quinolones are widely employed to treat shigellosis. However, quinolone resistance has already been reported, necessitating an understanding of the mechanisms of development of resistance. We demonstrate that high-level fluoroquinolone resistance of S. dysenteriae exposed to these antibiotics may occur in the absence of gyrA mutations and involve a proton motive force(pmf)-dependent efflux system.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
ID Code: | 102779 |
Deposited On: | 11 Mar 2017 13:22 |
Last Modified: | 11 Mar 2017 13:22 |
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