Histamine releasing activity of Carissa carandas roots (apocyaneceae)

Joglekar, S. N. ; Gaitonde, B. B. (1970) Histamine releasing activity of Carissa carandas roots (apocyaneceae) The Japanese Journal of Pharmacology, 20 (3). pp. 367-372. ISSN 0021-5198

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Related URL: http://dx.doi.org/10.1254/jjp.20.367


The roots of Carissa carandas L. known as Karaunda in Hindi are used in the treatment of helminthiasis (1). They are also used to assess the intensity of snake poisoning (2). Joshi and Boyce (3) have investigated the roots of another species Carissa congests and have reported the presence of glucoside. Since the roots of Carissa carandas are known to cause poisoning as a result of inadvertent contamination with other root material, it was decided to investigate the nature of the poisonous substance. In this report we have an evidence for the histamine liberating activity in the ethanol extract obtained from the roots.

Item Type:Article
Source:Copyright of this article belongs to Japanese Pharmacological Society.
ID Code:10256
Deposited On:04 Nov 2010 06:47
Last Modified:31 May 2011 11:52

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