Singh, Pankaj ; Gupta, Amit ; Jaiswal, Anil ; Dube, Anuradha ; Mishra, Saurabh ; Chaurasia, Manish K. (2011) Design and development of amphotericin B bearing polycaprolactone microparticles for macrophage targeting Journal of Biomedical Nanotechnology, 7 (1). pp. 50-51. ISSN 1550-7033
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Official URL: http://www.ingentaconnect.com/content/asp/jbn/2011...
Related URL: http://dx.doi.org/10.1166/jbn.2011.1196
Abstract
Antileishmanial efficacy of Amphotericin B bearing polycaprolactone (PCL) microparticles was investigated. The microparticles were prepared, optimized and subjected to in vitro characterization for shape (spherically structured), particle size (9.83±1.12 m), entrapment efficiency (43.54±3.98%) and in vitro drug release. The study revealed that PCL microparticles bearing Amphotericin B can be effectively used to target leishmanial parasites residing in macrophages.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Scientific Publishers. |
| Keywords: | Amphotericin B; Macrophage Targeting; Microparticles; Polycaprolactone |
| ID Code: | 101819 |
| Deposited On: | 11 Mar 2017 15:03 |
| Last Modified: | 11 Mar 2017 15:03 |
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