Enhanced antibacterial activity of bimetallic gold-silver core-shell nanoparticles at low silver concentration

Banerjee, Madhuchanda ; Sharma, Shilpa ; Chattopadhyay, Arun ; Ghosh, Siddhartha Sankar (2011) Enhanced antibacterial activity of bimetallic gold-silver core-shell nanoparticles at low silver concentration Nanoscale, 3 (12). pp. 5120-5125. ISSN 2040-3364

Full text not available from this repository.

Official URL: http://pubs.rsc.org/en/content/articlelanding/2011...

Related URL: http://dx.doi.org/10.1039/C1NR10703H

Abstract

Herein we report the development of bimetallic Au@Ag core–shell nanoparticles (NPs) where gold nanoparticles (Au NPs) served as the seeds for continuous deposition of silver atoms on its surface. The core–shell structure and morphology were examined by UV-Vis spectroscopy, transmission electron microscopy (TEM), energy dispersive X-ray (EDX) analysis and X-ray diffraction (XRD). The core–shell NPs showed antibacterial activity against both Gram negative (Escherichia coli and Pseudomonas aeruginosa) and Gram positive (Enterococcus faecalis and Pediococcus acidilactici) bacteria at low concentration of silver present in the shell, with more efficacy against Gram negative bacteria. TEM and flow cytometric studies showed that the core–shell NPs attached to the bacterial surface and caused membrane damage leading to cell death. The enhanced antibacterial properties of Au@Ag core–shell NPs was possibly due to the more active silver atoms in the shell surrounding gold core due to high surface free energy of the surface Ag atoms owing to shell thinness in the bimetallic NP structure.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:101185
Deposited On:16 Dec 2016 12:04
Last Modified:16 Dec 2016 12:04

Repository Staff Only: item control page