DNA replication during intra-erythrocytic stages of human malarial parasite Plasmodium falciparum

Abstract

Plasmodium falciparum, the causative agent of the most virulent form of human malaria, has deservingly held the candidature of being one of the most studied human pathogens. Here we attempt an overview of the studies probing one of the important aspects of DNA metabolism, that is, DNA replication in this parasite, focusing on the relatively well-characterized core components of chromosomal DNA replication in the asexual intra-erythrocytic stage.