Cu2+-embedded carbon nanoparticles as anticancer agents

Sk, Md Palashuddin ; Goswami, Upashi ; Ghosh, Siddhartha Sankar ; Chattopadhyay, Arun (2015) Cu2+-embedded carbon nanoparticles as anticancer agents Journal of Materials Chemistry B, 3 (28). pp. 5673-5677. ISSN 2050-750X

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Official URL: http://pubs.rsc.org/en/content/articlelanding/2015...

Related URL: http://dx.doi.org/10.1039/C5TB00567A

Abstract

We report the synthesis of luminescent carbon nanoparticles (93 ± 50 nm) embedded with Cu2+. It was observed that at a relatively low concentration of Cu2+ (2.55 ppm), cervical cancer HeLa cells died due to apoptosis induced by the nanoparticles. Also, generation of reactive oxygen species in the cells, in the presence of the composite nanoparticles, has been attributed to their killing. The luminescence of the carbon nanoparticles was used for imaging of the cells.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:100774
Deposited On:20 Dec 2016 07:09
Last Modified:20 Dec 2016 07:09

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