Surface complexation-based biocompatible magnetofluorescent nanoprobe for targeted cellular imaging

Bhandari, Satyapriya ; Khandelia, Rumi ; Pan, Uday Narayan ; Chattopadhyay, Arun (2015) Surface complexation-based biocompatible magnetofluorescent nanoprobe for targeted cellular imaging ACS Applied Materials & Interfaces, 7 (32). pp. 17552-17557. ISSN 1944-8244

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Official URL: http://pubs.acs.org/doi/abs/10.1021/acsami.5b04022

Related URL: http://dx.doi.org/10.1021/acsami.5b04022

Abstract

We report the synthesis of a magnetofluorescent biocompatible nanoprobe–following room temperature complexation reaction between Fe3O4-ZnS nanocomposite and 8-hydroxyquinoline (HQ). The composite nanoprobe exhibited high luminescence quantum yield, low rate of photobleaching, reasonable excited-state lifetime, luminescence stability especially in human blood serum, superparamagnetism and no apparent cytotoxicity. Moreover, the nanoprobe could be used for spatio-controlled cell labeling in the presence of an external magnetic field. The ease of synthesis and cell labeling in vitro make it a suitable candidate for targeted bioimaging applications.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
Keywords:Complexation Reaction; Magnetic Nanoparticle; Photoluminescence; Quantum Dots; Targeted Cellular Imaging
ID Code:100748
Deposited On:20 Dec 2016 06:56
Last Modified:20 Dec 2016 06:56

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