Chankeshwara, Sunay V. ; Chakraborti, Asit K. (2006) Catalyst-free chemoselective N-tert-butyloxycarbonylation of amines in water Organic Letters, 8 (15). pp. 3259-3262. ISSN 1523-7060
Full text not available from this repository.
Official URL: http://pubs.acs.org/doi/abs/10.1021/ol0611191
Related URL: http://dx.doi.org/10.1021/ol0611191
Abstract
Catalyst-free N-tert-butyloxycarbonylation of amines in water is reported. The N-t-Boc derivatives were formed chemoselectively without any isocyanate, urea, N,N-di-t-Boc, and O/S-t-Boc as side products. Chiral amines, esters of α-amino acids, and β-amino alcohol afforded optically pure N-t-Boc derivatives. Amino alcohol and 2-aminophenol afforded the N-t-Boc derivative without oxazolidinone formation. Selectivity was observed during competition of aromatic amine vs aliphatic amine, amine vs amino acid ester, amine vs amino alcohol, and primary amine vs secondary amine.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 100439 |
| Deposited On: | 19 Jan 2017 12:39 |
| Last Modified: | 19 Jan 2017 12:39 |
Repository Staff Only: item control page
