Srihari, P. ; Dutta, Palash ; Srinivasa Rao, R. ; Yadav, J. S. ; Chandrasekhar, S. ; Thombare, P. ; Mohapatra, J. ; Chatterjee, A. ; Jain, Mukul R. (2009) Solvent free synthesis of 1,5-disubstituted tetrazoles derived from Baylis Hillman acetates as potential TNF-α inhibitors Bioorganic & Medicinal Chemistry Letters, 19 (19). pp. 5569-5572. ISSN 0960-894X
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.bmcl.2009.08.047
Abstract
Solvent free multicomponent reaction of Baylis Hillman acetate, TMS azide and arylnitrile to produce 1,5-disubstituted tetrazole is described. Some of these tetrazoles are found to be potential TNF-α inhibitors.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Click Chemistry; Arthritis; Multicomponent; Michael Reaction; Baylis Hillman |
| ID Code: | 58914 |
| Deposited On: | 02 Sep 2011 03:36 |
| Last Modified: | 02 Sep 2011 03:36 |
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