Enantiomerically pure N-aryl-β-amino alcohols by enzymatic resolution

Sekar, Govindasamy ; Kamble, Rajesh M. ; Singh, Vinod K. (1999) Enantiomerically pure N-aryl-β-amino alcohols by enzymatic resolution Tetrahedron: Asymmetry, 10 (19). pp. 3663-3666. ISSN 0957-4166

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0957-4166(99)00401-2

Abstract

N-Aryl-β-amino acetates, obtained by opening epoxides with aromatic amines followed by acetylation of the hydroxyl group, were resolved using crude pig liver esterase (PLE) enzyme in DMSO in high enantiomeric excess.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:55304
Deposited On:18 Aug 2011 08:34
Last Modified:18 Aug 2011 08:34

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