Abnormalities in erythrocyte membrane band 3 in chronic myelogenous leukemia

Kundu, Manikuntala ; Basu, Joyoti ; Rakshit, Madan Mohan ; Chakrabarti, Parul (1989) Abnormalities in erythrocyte membrane band 3 in chronic myelogenous leukemia Biochimica et Biophysica Acta (BBA) - Biomembranes, 985 (1). pp. 97-100. ISSN 0005-2736

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000527...

Related URL: http://dx.doi.org/10.1016/0005-2736(89)90109-0

Abstract

The anion transport activities of erythrocytes from patients with chronic myelogenous leukemia (CML) and normal donors were comparable. In CML erythrocytes, significant reduction in the number of ankyrin-binding sites, present in the cytoplasmic domain of band 3, may lead to partial loss of cytoskeletal anchorage to the bilayer and account for their increased Con-A agglutinability and heat-sensitivity (Basu, J., Kundu, M., Rakshit, M.M. and Chakrabarti, P. (1988) Biochim. Biophys. Acta 945, 121–126).

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Band 3 Protein; Chronic Myelogenous Leukemia; Leukemia; Ankyrin Binding Site; (Human Blood)
ID Code:1672
Deposited On:05 Oct 2010 09:51
Last Modified:17 Jan 2011 08:36

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