Enantioselective synthesis of the C5–C23 segment of biselyngbyaside

Chandrasekhar, Srivari ; Rajesh, Gontla ; Naresh, Tumma (2013) Enantioselective synthesis of the C5–C23 segment of biselyngbyaside Tetrahedron Letters, 54 (3). pp. 252-255. ISSN 00404039

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Official URL: http://doi.org/10.1016/j.tetlet.2012.11.015

Related URL: http://dx.doi.org/10.1016/j.tetlet.2012.11.015

Abstract

Stereo and enantioselective synthesis of C5–C23 fragment of cytotoxic marine natural product biselyngbyaside is achieved using E-selective methyl lithium addition onto enyne, Crimmin’s acetate aldol reaction, Sharpless asymmetric epoxidation, and Julia–Kocienski olefination as the key steps.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Ltd
Keywords:Biselyngbyaside;Julia–Kocienski olefination;Crimmin’s acetate aldol reaction
ID Code:131346
Deposited On:06 Dec 2022 10:52
Last Modified:06 Dec 2022 10:52

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