Pal, Chandan ; Chakraborty, Tushar Kanti (2017) Synthesis of Amide-Linked Cyclic Dinucleotide Analogues with Pyrimidine Bases Asian Journal of Organic Chemistry, 6 (10). pp. 1421-1427. ISSN 21935807
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Official URL: http://doi.org/10.1002/ajoc.201700260
Related URL: http://dx.doi.org/10.1002/ajoc.201700260
Abstract
A convenient procedure has been developed for the synthesis of C2-symmetrical cyclic dinucleotide analogues that contain all-pyrimidine bases (cytosine, uracil and thymine) with amide bonds in place of natural phosphodiester linkages, starting from commercially available d-glucose diacetonide (GDA). The Vorbrüggen glycosylation of a common intermediate by using various pyrimidine bases was employed as the key step in the synthesis.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley & Sons, Inc |
| ID Code: | 131086 |
| Deposited On: | 02 Dec 2022 10:11 |
| Last Modified: | 02 Dec 2022 10:11 |
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