Neighboringortho-Hydroxy Group Directed Catalytic Asymmetric Triple Domino Reactions of Acetaldehyde with (E)-2-(2-Nitrovinyl)phenols

Ramachary, Dhevalapally B. ; Reddy, P. Srinivasa ; Prasad, M. Shiva (2014) Neighboringortho-Hydroxy Group Directed Catalytic Asymmetric Triple Domino Reactions of Acetaldehyde with (E)-2-(2-Nitrovinyl)phenols European Journal of Organic Chemistry, 2014 (15). pp. 3076-3081. ISSN 1434-193X

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Official URL: http://doi.org/10.1002/ejoc.201402182

Related URL: http://dx.doi.org/10.1002/ejoc.201402182

Abstract

The utilization of neighboring ortho-hydroxy group participation in the pretransition state of enamine/iminium-based triple domino Michael/aldol/oxa-Michael reactions catalyzed by (R)-DPPOTMS followed by Wittig and Michael/Wittig–Horner reactions is described. Enantiomerically pure chromanes and tetrahydro-6H-benzo[c]chromenes having three to four contiguous stereocenters are synthesized.

Item Type:Article
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ID Code:120667
Deposited On:03 Jul 2021 07:26
Last Modified:03 Jul 2021 07:26

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