Iron-Promoted Domino Annulation of α-Enolic Dithioesters with Ninhydrin under Solvent-Free Conditions: Chemoselective Direct Access to Indeno[1,2-b]thiophenes

Koley, Suvajit ; Chowdhury, Sushobhan ; Chanda, Tanmoy ; Ramulu, B. Janaki ; Nandi, Ganesh Chandra ; Singh, Maya Shankar (2014) Iron-Promoted Domino Annulation of α-Enolic Dithioesters with Ninhydrin under Solvent-Free Conditions: Chemoselective Direct Access to Indeno[1,2-b]thiophenes European Journal of Organic Chemistry, 2014 (25). pp. 5501-5508. ISSN 1434-193X

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Official URL: http://doi.org/10.1002/ejoc.201402276

Related URL: http://dx.doi.org/10.1002/ejoc.201402276

Abstract

The chemoselective synthesis of indeno[1,2-b]thiophenes was developed through the annulation of α-enolic dithioesters with ninhydrin under solvent-free conditions. This domino reaction sequence is highlighted by the use of inexpensive FeCl3·6H2O, its operational simplicity, a short reaction time, its functional-group tolerance, and the concomitant formation of two bonds and one thiophene ring.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
ID Code:119626
Deposited On:15 Jun 2021 08:00
Last Modified:15 Jun 2021 08:00

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