Cu-catalyzed sequential C–N bond formations: expeditious synthesis of tetracyclic indoloindol-3-ones

Kulkarni, Anand M. ; Srinivas, Kolluru ; Deshpande, Mukund V. ; Ramana, Chepuri V. (2016) Cu-catalyzed sequential C–N bond formations: expeditious synthesis of tetracyclic indoloindol-3-ones Organic Chemistry Frontiers, 3 (1). pp. 43-46. ISSN 2052-4129

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Official URL: http://pubs.rsc.org/en/content/articlelanding/2016...

Related URL: http://dx.doi.org/10.1039/C5QO00248F

Abstract

The tetracyclic indoloindol-3-one core has been forged from easily accessible 2,2′-bis-bromochalcones employing a reaction cascade comprising Cu-catalyzed SNAr with azide; nitrene C–H insertion and intramolecular Ullmann reaction with all three C–N bond formations in one-go.

Item Type:Article
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ID Code:105888
Deposited On:01 Feb 2018 16:52
Last Modified:01 Feb 2018 16:52

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