Items where Author is "Talukdar, Arindam"

Article

Goon, Sunny ; Shiu Chen Liu, Chinky ; Ghosh Dastidar, Uddipta ; Paul, Barnali ; Mukherjee, Suravi ; Sarkar, Himadri Sekhar ; Desai, Milie ; Jana, Rituparna ; Pal, Sourav ; Sreedevi, Namala Venkata ; Ganguly, Dipyaman ; Talukdar, Arindam (2024) Exploring the structural attributes of yoda1 for the development of new-generation Piezo1 agonist yaddle1 as a vaccine adjuvant targeting optimal T cell activation. Journal of Medicinal Chemistry, 67 (10). pp. 8225-8246. ISSN 0022-2623

Das, Nirmal ; Roy, Jayasree ; Patra, Binita ; Saunders, Eleanor ; Sarkar, Dipika ; Goon, Sunny ; Sinha, Bishnu Prasad ; Roy, Shreya ; Roy, Swarnali ; Sarif, Jafar ; Bandopadhyay, Purbita ; Barik, Subhasis ; Mukherjee, Suravi ; McNamara, Nicole ; Varghese, Swapna ; Simpson, Kaylene ; Baell, Jonathan ; McConville, Malcolm ; Ganguly, Dipyaman ; Talukdar, Arindam (2024) Hit-to-lead optimization of 2-aminoquinazolines as anti-microbial agents against Leishmania donovani. European Journal of Medicinal Chemistry, 269 . p. 116256. ISSN 0223-5234

Das, Nirmal ; Bhattacharya, Debomita ; Bandopadhyay, Purbita ; Dastidar, Uddipta Ghosh ; Paul, Barnali ; Rahaman, Oindrila ; Hoque, Israful ; Patra, Binita ; Ganguly, Dipyaman ; Talukdar, Arindam (2023) Mitigating hERG liability of toll‐like receptor 9 and 7 antagonists through structure‐based design. ChemMedChem, 18 (12). ISSN 1860-7179

Das, Nirmal ; Bandopadhyay, Purbita ; Roy, Swarnali ; Sinha, Bishnu Prasad ; Dastidar, Uddipta Ghosh ; Rahaman, Oindrila ; Pal, Sourav ; Ganguly, Dipyaman ; Talukdar, Arindam (2022) Development, optimization, and in vivo validation of new imidazopyridine chemotypes as dual TLR7/TLR9 antagonists through activity-directed sequential incorporation of relevant structural subunits. Journal of Medicinal Chemistry, 65 (17). pp. 11607-11632. ISSN 0022-2623

Pal, Sourav ; Ghosh Dastidar, Uddipta ; Ghosh, Trisha ; Ganguly, Dipyaman ; Talukdar, Arindam (2022) Integration of ligand-based and structure-based methods for the design of small-molecule TLR7 antagonists. Molecules, 27 (13). p. 4026. ISSN 1420-3049

Kundu, Biswajit ; Raychaudhuri, Deblina ; Mukherjee, Ayan ; Sinha, Bishnu Prasad ; Sarkar, Dipika ; Bandopadhyay, Purbita ; Pal, Sourav ; Das, Nirmal ; Dey, Debdeep ; Ramarao, Kantubhukta ; Nagireddy, Kasireddy ; Ganguly, Dipyaman ; Talukdar, Arindam (2021) Systematic optimization of potent and orally bioavailable purine scaffold as a dual inhibitor of toll-like receptors 7 and 9. Journal of Medicinal Chemistry, 64 (13). pp. 9279-9301. ISSN 0022-2623

Talukdar, Arindam ; Ganguly, Dipyaman ; Roy, Swarnali ; Das, Nirmal ; Sarkar, Dipika (2021) Structural evolution and translational potential for agonists and antagonists of endosomal toll-like receptors. Journal of Medicinal Chemistry, 64 (12). pp. 8010-8041. ISSN 0022-2623

Pal, Sourav ; Paul, Barnali ; Bandopadhyay, Purbita ; Preethy, Nagothy ; Sarkar, Dipika ; Rahaman, Oindrila ; Goon, Sunny ; Roy, Swarnali ; Ganguly, Dipyaman ; Talukdar, Arindam (2021) Synthesis and characterization of new potent TLR7 antagonists based on analysis of the binding mode using biomolecular simulations. European Journal of Medicinal Chemistry, 210 . p. 112978. ISSN 0223-5234

Kundu, Biswajit ; Sarkar, Dipayan ; Chowdhuri, Srijita Paul ; Pal, Sourav ; Das, Subhendu K. ; Das, Benu Brata ; Talukdar, Arindam (2020) Development of a metabolically stable topoisomerase I poison as anticancer agent European Journal of Medicinal Chemistry, 202 . p. 112551. ISSN 0223-5234

Kundu, Biswajit ; Das, Subhendu K. ; Paul Chowdhuri, Srijita ; Pal, Sourav ; Sarkar, Dipayan ; Ghosh, Arijit ; Mukherjee, Ayan ; Bhattacharya, Debomita ; Das, Benu Brata ; Talukdar, Arindam (2019) Discovery and Mechanistic Study of Tailor-Made Quinoline Derivatives as Topoisomerase 1 Poison with Potent Anticancer Activity Journal of Medicinal Chemistry, 62 (7). pp. 3428-3446. ISSN 0022-2623

Paul, Barnali ; Rahaman, Oindrila ; Roy, Swarnali ; Pal, Sourav ; Satish, Sohal ; Mukherjee, Ayan ; Ghosh, Amrit R. ; Raychaudhuri, Deblina ; Bhattacharya, Roopkatha ; Goon, Sunny ; Ganguly, Dipyaman ; Talukdar, Arindam (2018) Activity-guided development of potent and selective toll-like receptor 9 antagonists. European Journal of Medicinal Chemistry, 159 . pp. 187-205. ISSN 0223-5234

Roy, Swarnali ; Mukherjee, Ayan ; Paul, Barnali ; Rahaman, Oindrila ; Roy, Shounak ; Maithri, Gundaram ; Ramya, Bandaru ; Pal, Sourav ; Ganguly, Dipyaman ; Talukdar, Arindam (2017) Design and development of benzoxazole derivatives with toll-like receptor 9 antagonism. European Journal of Medicinal Chemistry, 134 . pp. 334-347. ISSN 0223-5234