Items where Author is "Srinivasan, Narayanaswamy"

Chakraborti, Sohini ; Chakraborty, Moubani ; Bose, Avipsa ; Srinivasan, Narayanaswamy ; Visweswariah, Sandhya S. (2021) Identification of Potential Binders of Mtb Universal Stress Protein (Rv1636) Through an in silico Approach and Insights Into Compound Selection for Experimental Validation Frontiers in Molecular Biosciences, 8 . ISSN 2296-889X

Bhagavat, Raghu ; Sankar, Santhosh ; Srinivasan, Narayanaswamy ; Chandra, Nagasuma (2018) An Augmented Pocketome: Detection and Analysis of Small-Molecule Binding Pockets in Proteins of Known 3D Structure Structure, 26 (3). pp. 499-512.e2. ISSN 0969-2126

Bhagavat, Raghu ; Srinivasan, Narayanaswamy ; Chandra, Nagasuma (2017) Deciphering common recognition principles of nucleoside mono/di and tri-phosphates binding in diverse proteins via structural matching of their binding sites Proteins: Structure, Function, and Bioinformatics, 85 (9). pp. 1699-1712. ISSN 0887-3585

Mudgal, Richa ; Srinivasan, Narayanaswamy ; Chandra, Nagasuma (2017) Resolving protein structure-function-binding site relationships from a binding site similarity network perspective Proteins: Structure, Function, and Bioinformatics, 85 (7). pp. 1319-1335. ISSN 0887-3585

Mudgal, Richa ; Sandhya, Sankaran ; Chandra, Nagasuma ; Srinivasan, Narayanaswamy (2015) De-DUFing the DUFs: deciphering distant evolutionary relationships of Domains of Unknown Function using sensitive homology detection methods Biology Direct, 10 . Article ID 38. ISSN 1745-6150

Ramakrishnan, Gayatri ; Ochoa-Montaño, Bernardo ; Raghavender, Upadhyayula S. ; Mudgal, Richa ; Joshi, Adwait G. ; Chandra, Nagasuma R. ; Sowdhamini, Ramanathan ; Blundell, Tom L. ; Srinivasan, Narayanaswamy (2015) Enriching the annotation of Mycobacterium tuberculosis H37Rv proteome using remote homology detection approaches: insights into structure and function Tuberculosis, 95 (1). pp. 14-25. ISSN 1472-9792

Ramakrishnan, Gayatri ; Chandra, Nagasuma R. ; Srinivasan, Narayanaswamy (2015) Recognizing drug targets using evolutionary information: implications for repurposing FDA-approved drugs against Mycobacterium tuberculosis H37Rv Molecular BioSystems, 11 (12). pp. 3316-3331. ISSN 1742-206X

Metri, Rahul ; Hariharaputran, Sridhar ; Ramakrishnan, Gayatri ; Anand, Praveen ; Raghavender, Upadhyayula S. ; Ochoa-Montaño, Bernardo ; Higueruelo, Alicia P. ; Sowdhamini, Ramanathan ; Chandra, Nagasuma R. ; Blundell, Tom L. ; Srinivasan, Narayanaswamy (2015) SInCRe—structural interactome computational resource for Mycobacterium tuberculosis Database, 2015 (1). Article ID bav060. ISSN 1758-0463

Vendra, Venkata P ; Balasubramanian, Dorairajan ; Chandani, Sushil ; Agarwal, Garima ; Srinivasan, Narayanaswamy ; Talla, Venu (2014) Effect of mutations on the structure and stability of lens βγ crystallins and their phenotypic relevance Investigative Ophthalmology & Visual Science, 55 (13). p. 4050.

Mudgal, Richa ; Sowdhamini, Ramanathan ; Chandra, Nagasuma ; Srinivasan, Narayanaswamy ; Sandhya, Sankaran (2014) Filling-in void and sparse regions in protein sequence space by protein-like artificial sequences enables remarkable enhancement in remote homology detection capability Journal of Molecular Biology, 426 (4). pp. 962-979. ISSN 0022-2836

Ramakrishnan, Gayatri ; Chandra, Nagasuma R. ; Srinivasan, Narayanaswamy (2014) From workstations to workbenches: Towards predicting physicochemically viable protein–protein interactions across a host and a pathogen IUBMB Life, 66 (11). pp. 759-774. ISSN 1521-6543

Srinivasan, Narayanaswamy ; Tanwar, Ajay Singh ; Goyal, Venuka Durani ; Choudhary, Deepanshu ; Panjikar, Santosh ; Anand, Ruchi (2013) Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis PLoS ONE, 8 (11). e77781. ISSN 1932-6203

Abraham, Edathara ; Vendra, Venkata Pulla Rao ; Agarwal, Garima ; Chandani, Sushil ; Talla, Venu ; Srinivasan, Narayanaswamy ; Balasubramanian, Dorairajan (2013) Structural Integrity of the Greek Key Motif in βγ-Crystallins Is Vital for Central Eye Lens Transparency PLoS ONE, 8 (8). e70336. ISSN 1932-6203

Agarwal, Garima ; Mahajan, Swapnil ; Srinivasan, Narayanaswamy ; de Brevern, Alexandre G. (2011) Identification of local conformational similarity in structurally variable regions of homologous proteins using protein blocks PLoS ONE, 6 (3). No PP. Given.. ISSN 1932-6203

Balasubramanian, Dorairajan ; Vendra, Venkata P ; Agarwal, Garima ; Srinivasan, Narayanaswamy (2011) Why Do N-terminal and C-terminal Domain Mutants of Human Gamma Crystallins Lead to Different Congenital Cataract Phenotypes? Investigative Ophthalmology & Visual Science, 52 (14). p. 4748.

Gelly, Jean-Christophe ; Joseph, Agnel Praveen ; Srinivasan, Narayanaswamy ; Brevern, Alexandre G. de. (2011) iPBA: a tool for protein structure comparison using sequence alignment strategies Nucleic Acids Research, 39 (2). pp. W18-W23. ISSN 0305-1048

Martin, Juliette ; Anamika, Krishanpal ; Srinivasan, Narayanaswamy (2010) Classification of protein kinases on the basis of both kinase and non-kinase regions PLoS ONE, 5 (5). No PP. Given.. ISSN 1932-6203

Malshetty, Vidyasagar ; Kurthkoti, Krishna ; China, Arnab ; Mallick, Bratati ; Yamunadevi, Subburaj ; Sang, Pau Biak ; Srinivasan, Narayanaswamy ; Nagaraja, Valakunja ; Varshney, Umesh (2010) Novel insertion and deletion mutants of RpoB that render mycobacterium smegmatis RNA polymerase resistant to rifampicin-mediated inhibition of transcription Microbiology, 156 (5). pp. 1565-1573. ISSN 1350-0872

Tyagi, Nidhi ; Anamika, Krishanpal ; Srinivasan, Narayanaswamy (2010) A framework for classification of prokaryotic protein kinases PLoS ONE, 5 (5). No PP. Given.. ISSN 1932-6203

Deshmukh, Krupa ; Anamika, Krishanpal ; Srinivasan, Narayanaswamy (2010) Evolution of domain combinations in protein kinases and its implications for functional diversity Progress in Biophysics and Molecular Biology, 102 (1). pp. 1-15. ISSN 0079-6107

Gadkari, Rupali A. ; Srinivasan, Narayanaswamy (2010) Prediction of protein-protein interactions in dengue virus coat proteins guided by low resolution cryoEM structures BMC Structural Biology, 10 (17). No PP. Given.. ISSN 1472-6807

Kumar, Anujith ; Bhosale, Manoj ; Reddy, Surendranath ; Srinivasan, Narayanaswamy ; Nandi, Dipankar (2009) Importance of non-conserved distal carboxyl terminal amino acids in two peptidases belonging to the M1 family: thermoplasma acidophilum tricorn interacting factor F2 and Escherichia coli peptidase N Biochimie, 91 (9). pp. 1145-1155. ISSN 0300-9084

Tyagi, Nidhi ; Swapna, Lakshmipuram Seshadri ; Mohanty, Smita ; Agarwal, Garima ; Gowri, Venkatraman Subramanian ; Anamika, Krishanpal ; Priya, Makani Leena ; Krishnadev, Oruganty ; Srinivasan, Narayanaswamy (2009) Evolutionary divergence of plasmodium falciparum: sequences, protein-protein interactions, pathways and processes Infectious Disorders - Drug Targets, 9 (3). pp. 257-271. ISSN 1871-5265

Agarwal, Garima ; Rajavel, Malligarjunan ; Gopal, Balasubramanian ; Srinivasan, Narayanaswamy (2009) Structure-based phylogeny as a diagnostic for functional characterization of proteins with a cupin fold PLoS ONE, 4 (5). No PP. Given.. ISSN 1932-6203

Anamika, Krishanpal ; Garnier, Nicolas ; Srinivasan, Narayanaswamy (2009) Functional diversity of human protein kinase splice variants marks significant expansion of human kinome BMC Genomics, 10 (622). No PP. Given.. ISSN 1471-2164

Kandathil, Abraham Joseph ; Joseph, Agnel Praveen ; Kannangai, Rajesh ; Srinivasan, Narayanaswamy ; Abraham, Oriapadickal Cherian ; Pulimood, Susanne Alexander ; Sridharan, Gopalan (2009) HIV reverse transcriptase: structural interpretation of drug resistant genetic variants from India Bioinformation, 4 (1). pp. 36-45. ISSN 0973-8894

Sandhya, Sankaran ; Rani, Saane Sudha ; Pankaj, Barah ; Govind, Madabosse Kande ; Offmann, Bernard ; Srinivasan, Narayanaswamy ; Sowdhamini, Ramanathan (2009) Length variations amongst protein domain superfamilies and consequences on structure and function PLoS ONE, 4 (3). No PP. Given.. ISSN 1932-6203

Roy, Ambrish ; Srinivasan, Narayanaswamy ; Gowri, Venkatraman S. (2009) Molecular and structural basis of drift in the functions of closely-related homologous enzyme domains: implications for function annotation based on homology searches and structural genomics In Silico Biology, 9 (1-2). pp. S41-S55. ISSN 1386-6338

Kandathil, Abraham Joseph ; Joseph, Agnel Praveen ; Kannangai, Rajesh ; Srinivasan, Narayanaswamy ; Abraham, Oriapadickal Cherian ; Pulimood, Susanne Alexander ; Sridharan, Gopalan (2009) Structural basis of drug resistance by genetic variants of HIV type 1 clade C protease from India AIDS Research and Human Retroviruses, 25 (5). pp. 511-519. ISSN 0889-2229

Anamika, Krishanpal ; Martin, Juliette ; Srinivasan, Narayanaswamy (2008) Comparative kinomics of human and chimpanzee reveal unique kinship and functional diversity generated by new domain combinations BMC Genomics, 9 . No PP. Given.. ISSN 1471-2164

Talla, Venu ; Srinivasan, Narayanaswamy ; Balasubramanian, Dorairajan (2008) Visualization of in Situ intracellular aggregation of two cataract-associated human γ-crystallin mutants: lose a tail, lose transparency Investigative Ophthalmology & Visual Science, 49 (8). pp. 3483-3490. ISSN 0146-0404

Krishna Pantakani, D. V. ; Swapna, Lakshmipuram S. ; Srinivasan, Narayanaswamy ; Mannan, Ashraf U. (2008) Spastin oligomerizes into a hexamer and the mutant spastin (E442Q) redistribute the wild-type spastin into filamentous microtubule Journal of Neurochemistry, 106 (2). pp. 613-624. ISSN 0022-3042

Sandhya, Sankaran ; Pankaj, Barah ; Govind, Madabosse Kande ; Offmann, Bernard ; Srinivasan, Narayanaswamy ; Sowdhamini, Ramanathan (2008) CUSP: an algorithm to distinguish structurally conserved and unconserved regions in protein domain alignments and its application in the study of large length variations BMC Structural Biology, 8 (28). No PP. Given.. ISSN 1472-6807

Jhingran, Anupam ; Padmanabhan, Prasad K. ; Singh, Sushma ; Anamika, Krishanpal ; Bakre, Abhijeet A. ; Bhattacharya, Sudha ; Bhattacharya, Alok ; Srinivasan, Narayanaswamy ; Madhubala, Rentala (2008) Characterization of the Entamoeba histolytica ornithine decarboxylase-like enzyme PLoS Neglected Tropical Diseases, 2 (1). pp. e115_1-e115_10. ISSN 1935-2735

Krishnadev, Oruganty ; Srinivasan, Narayanaswamy (2008) A dataintegration approach to predict host-pathogen protein-protein interactions: application to recognize protein interactions between human and a malarial parasite In Silico Biology, 8 (3-4). pp. 235-250. ISSN 1386-6338

Tyagi, Manoj ; Gowri, Venkataraman S. ; Srinivasan, Narayanaswamy ; de Brevern, Alexandre G. ; Offmann, Bernard (2006) A substitution matrix for structural alphabet based on structural alignment of homologous proteins and its applications Proteins: Structure, Function, and Bioinformatics, 65 (1). pp. 32-39. ISSN 0887-3585

Sharma, Kirti ; Gupta, Meetu ; Krupa, Ananth ; Srinivasan, Narayanaswamy ; Singh, Yogendra (2006) EmbR, a regulatory protein with ATPase activity, is a substrate of multiple serine/threonine kinases and phosphatase in Mycobacterium tuberculosis FEBS Journal, 273 (12). pp. 2711-2721. ISSN 1742-464X

Talla, Venu ; Narayanan, Chitra ; Srinivasan, Narayanaswamy ; Balasubramanian, Dorairajan (2006) Mutation causing self-aggregation in human γC-crystallin leading to congenital cataract Investigative Ophthalmology and Visual Science, 47 . pp. 5212-5217. ISSN 0146-0404

Padmanabhan, Prasad K. ; Mukherjee, Angana ; Singh, Sushma ; Chattopadhyaya, Swati ; Gowri, Venkataraman S. ; Myler, Peter J. ; Srinivasan, Narayanaswamy ; Madhubala, Rentala (2005) Glyoxalase I from Leishmania donovani: a potential target for anti-parasite drug Biochemical and Biophysical Research Communications, 337 (4). pp. 1237-1248. ISSN 0006-291X

Bhadra, Rana ; Srinivasan, Narayanaswamy ; Pandit, Shashi B. (2005) A new domain family in the superfamily of alkaline phosphatases In Silico Biology, 5 (4). pp. 379-387. ISSN 1386-6338

Namboori, Seema ; Mhatre, Natasha ; Sujatha, Sentivel ; Srinivasan, Narayanaswamy ; Pandit, Shashi Bhushan (2004) Enhanced functional and structural domain assignments using remote similarity detection procedures for proteins encoded in the genome of Mycobacterium tuberculosis H37Rv Journal of Biosciences, 29 (3). pp. 245-259. ISSN 0250-5991

Praseeda, Mullasseril ; Pradeep, Kurup K. ; Krupa, Ananth ; Krishna, S. Sri ; Leena, Suseela ; Kumar, R. Rajeev ; Cheriyan, John ; Myadevi, Madhavan ; Srinivasan, Narayanaswamy ; Omkumar, Ramakrishnapillai V. (2004) Influence of a mutation in the ATP-binding region of Ca²⁺/calmodulindependent protein kinase II on its interaction with peptide substrates Biochemical Journal, 378 . pp. 391-397. ISSN 0006-2936

Namboori, Seema ; Srinivasan, Narayanaswamy ; Pandit, Shashi B. (2004) Recognition of remotely related structural homologues using sequence profiles of aligned homologous protein structures In Silico Biology, 4 (4). pp. 445-460. ISSN 1386-6338

Pudi, Renuka ; Abhiman, Saraswathi ; Srinivasan, Narayanaswamy ; Das, Saumitra (2003) Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by specific interaction of independent regions of human La autoantigen Journal of Biological Chemistry, 278 (14). pp. 12231-12240. ISSN 0021-9258

Sehrawat, Seema ; Srinivasan, Narayanaswamy ; Gopinathan, Karumathil P. (2002) Functional characterization and structural modelling of late gene expression factor 4 from Bombyx mori nucleopolyhedrovirus Biochemical Journal, 368 (1). pp. 159-169. ISSN 0264-6021

Gupta, Surbhi ; Pandit, Shashi Bhushan ; Srinivasan, Narayanaswamy ; Chatterji, Dipankar (2002) Proteomics analysis of carbon-starved Mycobacterium smegmatis: induction of Dps-like protein Protein Engineering Design and Selection, 15 (6). pp. 503-511. ISSN 1741-0126

Newbold, Richard J. ; Deery, Evelyne C. ; Walker, Caroline E. ; Wilkie, Susan E. ; Srinivasan, Narayanaswamy ; Hunt, David M. ; Bhattacharya, Shomi S. ; Warren, Martin J. (2001) The destabilization of human GCAP1 by a proline to leucine mutation might cause cone-rod dystrophy Human Molecular Genetics, 10 (1). pp. 47-54. ISSN 0964-6906

May, Alex C. W. ; Johnson, Mark S. ; Rufino, Stephen D. ; Wako, Hiroshi ; Zhu, Zhan-Yang ; Sowdhamini, Ramanathan ; Srinivasan, Narayanaswamy ; Rodionov, Michael A. ; Blundell, Tom L. ; Dover, G. A. (1994) The recognition of protein structure and function from sequence: adding value to genome data [and discussion] Philosophical Transactions: Biological Sciences, 344 (1310). pp. 373-381. ISSN 0962-8436

Emsley, Jonas ; White, Helen E. ; O'Hara, Bernard P. ; Oliva, Glaucius ; Srinivasan, Narayanaswamy ; Tickle, Ian J. ; Blundell, Tom L. ; Pepys, Mark B. ; Wood, Steve P. (1994) Structure of pentameric human serum amyloid P component Nature, 367 . pp. 338-345. ISSN 0028-0836

Johnson, Mark S. ; Srinivasan, Narayanaswamy ; Sowdhamini, Ramanathan ; Blundell, Tom L. (1994) Knowledge-based protein modeling Critical Reviews in Biochemistry and Molecular Biology, 29 (1). pp. 1-68. ISSN 1040-9238

Ramakrishnan, Gayatri ; Chandra, Nagasuma ; Srinivasan, Narayanaswamy Exploring anti-malarial potential of FDA approved drugs: an in silico approach Malaria Journal, 16 (1). Article ID 290. ISSN 1475-2875

Bhagavat, Raghu ; Kim, Heung-Bok ; Kim, Chang-Yub ; Terwilliger, Thomas C. ; Mehta, Dolly ; Srinivasan, Narayanaswamy ; Chandra, Nagasuma A genome-wide structure-based survey of nucleotide binding proteins in M. tuberculosis Scientific Reports, 7 . Article ID 12489. ISSN 2045-2322