Rajan, M. T. ; Champion, D. ; Kumar, C. S. ; Vishnuvardhan, D. ; Jagannatha Rao, K. S. ; M. A., Viswamitra (1996) Interaction of Co, Mn, Mg and Al with d(GCGTACGC): a spectroscopic study Molecular Biology reports, 22 (1). pp. 47-52. ISSN 0301-4851
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Official URL: http://www.springerlink.com/content/qv0h4617528p74...
Related URL: http://dx.doi.org/10.1007/BF00996304
Abstract
Spectroscopic study on the interactions of trace elements Co, Mn, Mg and Al with d(GCGTACGC) indicated the following: Al and Mg did not alter Tm values. Mn enhanced Tm at lower concentration and decreased it at higher concentrations. Interestingly Co at higher concentration elevated the Tm. These studies also showed lower concentrations of Mn displaced EtBr, whereas Al could displace it at higher ionic strength. Mg and Co displaced EtBr fluorescence at moderate concentrations. The binding constant values and CD spectra clearly indicated strong binding of these elements to DNA.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer. |
| Keywords: | DNA; Interaction; Spectroscopy and Trace Elements |
| ID Code: | 72783 |
| Deposited On: | 03 Dec 2011 11:59 |
| Last Modified: | 03 Dec 2011 11:59 |
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