Famulok, Michael ; Verma, Sandeep (2002) In vivo-applied functional RNAs as tools in proteomics and genomics research Trends in Biotechnology, 20 (11). pp. 462-466. ISSN 0167-7799
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/S0167-7799(02)02063-2
Abstract
Non-natural, functional RNA molecules, such as short interfering (si) RNAs, aptazymes, maxizymes and intramers, allow modulation of gene function at the mRNA or protein level. This review discusses recent advances made in the expression and application of these functional RNAs and illustrates how engineered, intracellularly active RNAs can serve as promising tools for understanding the function of genes and their protein products or as potential therapeutic agents.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | RNA Interference; Proteomics; Function; Genomics; Protein; Aptazyme; Maxizyme; Intramer; Biotechnology; Bioinformatics; Genetics; Cell Biology; Techniques & Methods |
| ID Code: | 66245 |
| Deposited On: | 21 Oct 2011 09:42 |
| Last Modified: | 21 Oct 2011 09:42 |
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