Enantioselective synthesis of (+)-4-demethoxy-1, 4-dimethyldaunomycinone

Kotha, Sambasivarao ; Stoodley, Richard J. (2002) Enantioselective synthesis of (+)-4-demethoxy-1, 4-dimethyldaunomycinone Bioorganic & Medicinal Chemistry, 10 (3). pp. 621-624. ISSN 0968-0896

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0968-0896(01)00316-9

Abstract

(+)-4-Demethoxy-1,4-dimethyldaunomycinone 1 was synthesized using a convergent approach. Here, the key tetracyclic compound 10 was assembled by way of a Diels-Alder reaction using the sugar-based diene 8 and the quinizarin-related dienophile 7.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:65185
Deposited On:15 Oct 2011 11:39
Last Modified:15 Oct 2011 11:39

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