LiClO4-catalysed C-alkylation of pyrrole and indoles with aziridines and epoxides

Yadav, J. S. ; Reddy, B. V. S. ; Parimala, G. (2003) LiClO4-catalysed C-alkylation of pyrrole and indoles with aziridines and epoxides Journal of Chemical Research, 2003 (2). pp. 78-81. ISSN 0308-2342

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Official URL: http://www.ingentaconnect.com/content/stl/jcr/2003...

Related URL: http://dx.doi.org/10.3184/030823403103173020

Abstract

Aryl-N-tosylaziridines and epoxides smoothly undergo ring-opening with pyrrole and indoles in the presence of 5M lithium perchlorate in diethyl ether (LPDE) at ambient temperature to afford the corresponding 2- and 3-alkylated pyrroles and 3-alkylated indoles in high yields with high selectivity. LiOTf is also found to be an effective catalyst for this transformation.

Item Type:Article
Source:Copyright of this article belongs to Science Reviews 2000 Ltd.
Keywords:Lithium Perchlorate; Lithium Triflate; Aziridines
ID Code:63244
Deposited On:28 Sep 2011 03:21
Last Modified:28 Sep 2011 03:21

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