Subba Reddy, B. V. ; Begum, Zubeda ; Jayasudhan Reddy, Y. ; Yadav, J. S. (2010) Pd(OAc)2-catalyzed C-H activation of indoles: a facile synthesis of 3-cyanoindoles Tetrahedron Letters, 51 (25). pp. 3334-3336. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2010.04.086
Abstract
Indoles undergo smooth cyanation with CuCN in the presence of 20 mol % Pd(OAc)2 and 40 mol % CuBr2 in DMF to produce a wide range of the corresponding 3-cyanoindoles in good yields with high regioselectivity.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Indoles; Regioselective Cyanation; Pd(OAc)2; 3-Cyanoindoles; C-H Activation |
| ID Code: | 63147 |
| Deposited On: | 28 Sep 2011 03:48 |
| Last Modified: | 28 Sep 2011 03:48 |
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