Yadav, Jhillu Singh ; Chandrakanth, Dandekar ; Rao, Yerragorla Gopala ; Ravindar, Kontham ; Subba Reddy, Basi V. (2010) The stereoselective total synthesis of (6S)-5, 6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one via Prins cyclization Helvetica Chimica Acta, 93 (7). pp. 1432-1438. ISSN 0018-019X
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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/hlca.20...
Related URL: http://dx.doi.org/10.1002/hlca.200900414
Abstract
The stereoselective total synthesis of an antiproliferative and antifungal α-pyrone natural product (6S)-5,6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one is described. The key steps involved are the Prins cyclization, Mitsunobu reaction, and ring-closing metathesis reaction.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| Keywords: | 2H-Pyran-2-ones; Prins cyclization; Mitsunobu Reaction; Ring-closing Metathesis (RCM) |
| ID Code: | 63143 |
| Deposited On: | 28 Sep 2011 03:49 |
| Last Modified: | 28 Sep 2011 03:49 |
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